↑ Curry, Stephen H. (1993). "PHARMACOKINETICS OF ANTIPSYCHOTIC DRUGS". Antipsychotic Drugs and their Side-Effects. Elsevier. m/s. 127–144. doi:10.1016/b978-0-12-079035-7.50015-4. ISBN978-0-12-079035-7. The elimination half-life measures the kinetics of loss of drug from the body as a whole once all distribution equilibria have been achieved.
1 2 Dasgupta, Amitava; Krasowski, Matthew D. (2020). "Pharmacokinetics and therapeutic drug monitoring". Therapeutic Drug Monitoring Data. Elsevier. m/s. 1–17. doi:10.1016/b978-0-12-815849-4.00001-3. ISBN978-0-12-815849-4. The half-life of a drug is the time required for the serum concentration to be reduced by 50%. Once the half-life of the drug is known, the time required for clearance can be estimated. Approximately 97% of the drug is eliminated by 5 halflives, while ~99% is eliminated by 7 half-lives.
↑ Toutain, P. L.; Bousquet-Melou, A. (2004). "Plasma terminal half-life" (PDF). Journal of Veterinary Pharmacology and Therapeutics. 27 (6): 427–439. doi:10.1111/j.1365-2885.2004.00600.x. PMID15601438. Diarkibkan daripada yang asal (PDF) pada 2020-02-20. Following i.v. administration, the terminal half-life is the time required for plasma/blood concentration to decrease by 50% after pseudo-equilibrium of distribution has been reached; then, terminal half-life is computed when the decrease in drug plasma concentration is due only to drug elimination, and the term ‘elimination half-life’ is applicable. Therefore, it is not the time necessary for the amount of the administered drug to fall by one half.
↑ Nordberg, Gunnar (2007). Handbook on the toxicology of metals. Amsterdam: Elsevier. m/s. 119. ISBN978-0-12-369413-3.
↑ Silk, Kenneth R.; Tyrer, Peter J. (2008). Cambridge textbook of effective treatments in psychiatry. Cambridge, UK: Cambridge University Press. m/s. 295. ISBN978-0-521-84228-0.
